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| Nano-yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering |
| Jun Li, Wei Liu, Anlin Yin, Jinglei Wu, Salem S. Al-Deyab, Mohamed El-Newehy, Xiumei Mo |
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Abstract In this paper, novel nano-yarn reinforced scaffolds were fabricated and further biomineralized by submerging in 10 simulated Body Fluid (SBF). The compressive strength of P(LLA-CL)/Silk Fibroin (SF) nano-yarns reinforced scaffold was 1.72+-0.50 MPa and its porosity is 82.8%. Fourier Transform Infrared Spectrum (FTIR) and X-ray Diffraction (XRD) data confirmed the mineral phase was made of Hydroxyapatite (HA). MC3T3-E1 cell proliferation and differentiation on the scaffolds were evaluated. In vitro biological evaluation showed that HA coated scaffolds provided higher cell proliferation efficiency (t-test, P < 0.05) than uncoated scaffolds.
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| Cite this article: |
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Jun Li,Wei Liu,Anlin Yin, et al. Nano-yarns Reinforced Silk Fibroin Composites Scaffold for Bone Tissue Engineering[J]. , 2012, 5(2): 169-179.
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2012, Vol. 5 
