In the context of an ageing population, the research and development of elderly women’s clothing has been widely discussed, and its clothing market has a good prospect. However, research on the design of T-shirts is mainly aimed at young people, and there is still a lack of research on the design of spring and autumn T-shirts specifically for elderly women. This paper conducts on-site research to understand the physical characteristics and clothing needs of elderly women and selects elderly obese women as the research object. The spring and autumn T-shirts are designed using a fake two-piece structural style combined with imitation woven, knitted fabric, and the rationality of the spring and autumn T-shirt design is verified through 3D virtual trial wear.